$75.00
Ipamorelin is a peptide that interacts with the ghrelin/growth hormone secretagogue receptor. This interaction makes it a potent and selective growth hormone (GH) secretagogue. Unlike other GH secretagogues, Ipamorelin specifically targets the growth hormone system without affecting the secretion of other hormones like ACTH, prolactin, and cortisol. This level of selectivity makes it a good choice for researchers. They can study how growth hormone is released and its potential uses in therapy.
Ipamorelin is a synthetic pentapeptide designed to target the ghrelin/growth hormone secretagogue receptor (GHS-R) with exceptional selectivity. As a specific growth hormone (GH) secretagogue, it is studied for its ability to promote GH release. It does this without affecting other hormonal pathways like ACTH, prolactin, or cortisol. This precision makes Ipamorelin a reliable compound in growth hormone regulation research. It is widely used to study endocrine signaling and metabolic responses in controlled lab conditions.
Peptide Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Formula: C38H49N9O5
Molecular Weight: 711.86 g/mol
CAS Number: 170851-70-4
PubChem CID: 9831669
Purity: ≥99% (HPLC and MS verified)
Classification: Research Use Only (RUO)
The structural design of Ipamorelin allows selective binding to ghrelin receptors, triggering GH secretion through the hypothalamic-pituitary axis while avoiding off-target effects. This balance of potency and safety has made it a key compound in hormonal and metabolic peptide research.
Ipamorelin acts by mimicking ghrelin—the body’s natural growth hormone secretagogue. Upon binding to the GHS-R1a receptor, it stimulates pulsatile growth hormone release from the anterior pituitary. Unlike traditional GHRPs (such as GHRP-6 or Hexarelin), Ipamorelin’s mechanism avoids stimulating cortisol or prolactin, offering cleaner, more controlled results in experimental designs.
This mechanism provides a valuable model for studying how GH impacts cellular repair, metabolic efficiency, and muscle preservation. It also makes Ipamorelin a strong candidate for comparative research in GH modulation versus other secretagogues like CJC-1295.
Ipamorelin is versatile and relevant to many experimental models. It is particularly useful in studies on bone density, muscle metabolism, and recovery from glucocorticoid-induced side effects. It is also studied in metabolic and endocrine disorders where GH signaling plays a regulatory role.
1. Bone Density and Osteogenesis Research
Laboratory studies have observed that Ipamorelin can stimulate osteoblast activity and counteract steroid-induced bone loss. In glucocorticoid-treated models, the peptide supports bone matrix formation and mineralization, providing a framework for exploring GH-mediated bone restoration mechanisms.
2. Muscle Growth and Anti-Catabolic Pathways
Ipamorelin is frequently investigated in muscle preservation research. It has been shown to influence nitrogen retention and prevent muscle catabolism, particularly under conditions of corticosteroid stress. These findings make it a vital reference in the study of anabolic signaling and GH receptor dynamics.
3. Glucocorticoid Counteraction Models
Prolonged glucocorticoid therapy often leads to tissue degradation and impaired recovery. Ipamorelin’s selective action has been shown to reduce the negative effects of corticosteroids in animal models. It helps maintain lean tissue and improves metabolic balance without impacting adrenal function.
4. Metabolic and Insulin Sensitivity Studies
In diabetic and metabolic models, Ipamorelin has been shown to modulate insulin release and glucose utilization. These studies explore how GH secretagogues may influence glycemic regulation, providing insight into peptide-mediated metabolic optimization.
5. Gastrointestinal Motility Research
Ipamorelin has demonstrated potential benefits in studies of postoperative ileus (POI), a temporary impairment of gastrointestinal function following surgery. Research has shown improvements in intestinal motility and recovery time, though this remains a developing area of investigation.
Beyond hormonal research, Ipamorelin is being explored as a molecular imaging probe for positron emission tomography (PET) and related diagnostic modalities. It has a strong binding affinity for the ghrelin receptor. This property can help visualize receptor activity. This is relevant in conditions such as cardiovascular dysfunctions and certain tumor expressions. This field continues to evolve as researchers look for novel diagnostic and therapeutic applications.
Every batch of Amino Pharm’s Ipamorelin peptide undergoes analysis using HPLC and Mass Spectrometry. This process verifies the sequence, molecular weight, and ensures purity of at least 99%. All results are detailed in a Certificate of Analysis (COA) available with each order, ensuring compliance, reproducibility, and traceability.
Our research peptides USA are synthesized in U.S.-based, GMP-aligned facilities that maintain precision manufacturing standards. Peptides are securely stored and shipped under temperature-controlled conditions to preserve stability throughout transport.
Ipamorelin is supplied for in-vitro research and educational purposes only. It is not approved for therapeutic or human use. All descriptive content refers to biochemical, analytical, and preclinical research applications in accordance with FDA guidelines for Research Use Only (RUO) classification.
Amino Pharm emphasizes integrity, transparency, and data reproducibility. This approach gives researchers reliable access to verified, COA-verified peptides. These peptides meet the highest standards of synthesis and analysis.
What is Ipamorelin studied for?
Ipamorelin is primarily studied for its role as a selective growth hormone secretagogue. Research focuses on its influence over muscle growth, bone formation, and recovery from glucocorticoid-induced catabolism.
How does Ipamorelin differ from other GH secretagogues?
Ipamorelin is more selective for growth hormone (GH) release than GHRP-6 or Hexarelin. It does not stimulate cortisol or prolactin. This makes Ipamorelin suitable for precise endocrine research.
Is Ipamorelin available for human consumption?
No. Ipamorelin is classified as a research-grade peptide and is not approved for medical or therapeutic use.
Can I buy Ipamorelin online?
Yes, researchers can buy research peptides online directly from Amino Pharm. Each product includes verified COA documentation and secure, temperature-regulated shipping.
How is peptide purity verified?
Purity is confirmed through HPLC and LC-MS analysis, ensuring molecular accuracy and consistency for every batch.
What makes Amino Pharm’s Ipamorelin unique?
Amino Pharm’s Ipamorelin is synthesized in the U.S., verified by a Certificate of Analysis, and batch tested. This ensures reliability and consistency for laboratory studies on growth hormone pathways.
Ipamorelin is a precise and selective tool for studying growth hormone release and ghrelin receptor signaling. Its hormonal profile is clean. The data is consistent. Its high purity makes it a preferred peptide. This peptide is used in endocrine, metabolic, and regenerative research. For scientists seeking trusted laboratory peptides that meet rigorous quality standards, Amino Pharm delivers reliability, consistency, and full documentation to support validated research outcomes.
